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001			6473916
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008			051103s2007 fluaf b 001 0 eng
010			_a 2005056902
015			_aGBA614519 _2bnb
016	7		_a013380737 _2Uk
020			_a9781584886426
035			_a(OCoLC)ocm62325140
035			_a(NNC)6473916
040			_aDLC _cDLC _dBAKER _dUKM _dC#P _dYDXCP _dOCLCQ _dIG# _dYUS _dPUL _dAGL _dBTCTA _dCUS _dOrLoB-B
042			_apcc
050	0	0	_aQH324.2 _b.A46 2007
070	0		_aQH324.2 _b.A46 2007
082	0	0	_a570.285 _222 _bALO-I
100	1		_aAlon, Uri
245	1	3	_aIntroduction to systems biology : _bdesign principles of biological circuits _cUri Alon.
260			_aBoca Raton, FL : _bChapman & Hall/CRC, _c©2007.
300			_axvi, 301 p., [4] p. of plates : _bill. (some col.) ; _c26 cm.
490	1		_aChapman & Hall/CRC mathematical and computational biology series ; _v10
504			_aIncludes bibliographical references (p. 271-293) and index.
505	0	0	_gCh. 1. _tIntroduction -- _gCh. 2. _tTranscription networks : basic concepts -- _gCh. 3. _tAutoregulation : a network motif -- _gCh. 4. _tThe feed-forward loop network motif -- _gCh. 5. _tTemporal programs and the global structure of transcription networks -- _gCh. 6. _tNetwork motifs in developmental, signal transduction, and neuronal networks -- _gCh. 7. _tRobustness of protein circuits : the example of bacterial chemotaxis -- _gCh. 8. _tRobust patterning in development -- _gCh. 9. _tKinetic proofreading -- _gCh. 10. _tOptimal gene circuit design -- _gCh. 11. _tDemand rules for gene regulation -- _gCh. 12. _tEpilogue : simplicity in biology -- _gApp. A. _tThe input function of a gene : Michaelis-Menten and Hill equations -- _gApp. B. _tMulti-dimensional input functions -- _gApp. C. _tGraph properties of transcription networks -- _gApp. D. _tCell-cell variability in gene expression.
520	1		_a"An Introduction to Systems Biology: Design Principles of Biological Circuits builds a foundation for the intuitive understanding of general principles in biology. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models."--BOOK JACKET.
650		0	_aComputational biology.
650		0	_aBiological systems _xMathematical models.
650		2	_aSystems Biology _xmethods.
830		0	_aChapman and Hall/CRC mathematical & computational biology series ; _v10.
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0654/2005056902-d.html
900			_bTOC
942			_2ddc _cBK _016
948	1		_a20080311 _bc _cks26 _dMPS
948	2		_a20080331 _ba _cks26 _dMPS
948	2		_a20130207 _ba _crad1 _dMPS
999			_c7183 _d7183