000 | 03370nam a22006015i 4500 | ||
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001 | 978-981-99-2423-3 | ||
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_a9789819924233 _9978-981-99-2423-3 |
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024 | 7 |
_a10.1007/978-981-99-2423-3 _2doi |
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_a570.285 _223 |
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_aPoluri, Krishna Mohan. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
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245 | 1 | 0 |
_aProtein-Protein Interactions _h[electronic resource] : _bPathophysiological and Therapeutic Aspects: Volume II / _cby Krishna Mohan Poluri, Khushboo Gulati, Deepak Kumar Tripathi, Nupur Nagar. |
250 | _a1st ed. 2023. | ||
264 | 1 |
_aSingapore : _bSpringer Nature Singapore : _bImprint: Springer, _c2023. |
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300 |
_aXVIII, 428 p. 1 illus. _bonline resource. |
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_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
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_aonline resource _bcr _2rdacarrier |
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_atext file _bPDF _2rda |
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505 | 0 | _aChapter 1: Protein Networks in Human Disease -- Chapter 2: Protein-Protein Interactions in Cancer -- Chapter 3: Protein-Protein Interactions in Neurodegenerative Diseases -- Chapter 4: Protein-Protein Interactions in Immune Disorders and Inflammation -- Chapter 5: PPIs in Host-Pathogen Interactions -- Chapter 6: Drug Design methods to regulate protein-protein interactions -- Chapter 7: Small molecule inhibitors of Protein-Protein Interactions as Therapeutics. | |
520 | _aThe second volume of the book-Protein-Protein Interactions (PPIs) provides an overview of various protein-protein interactions (PPIs) that are involved in various human diseases including cancer, neurodegenerative diseases, immune diseases, and inflammation. It summarizes the structure and ligand-based drug designing approaches for the discovery of small molecules that can inhibit PPIs in these diseases. The book discusses different computational and experimental tools that are used to determine the anomalous interactions underlying the diseases. Lastly, it also reviews the classical interactions between pathogens and hosts that are responsible for the pathophysiology of infectious diseases. | ||
650 | 0 | _aBioinformatics. | |
650 | 0 | _aLife sciences. | |
650 | 0 |
_aMedicine _xResearch. |
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650 | 0 |
_aBiology _xResearch. |
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650 | 0 | _aNeurosciences. | |
650 | 1 | 4 | _aBioinformatics. |
650 | 2 | 4 | _aLife Sciences. |
650 | 2 | 4 | _aBiomedical Research. |
650 | 2 | 4 | _aNeuroscience. |
700 | 1 |
_aGulati, Khushboo. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
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700 | 1 |
_aTripathi, Deepak Kumar. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
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700 | 1 |
_aNagar, Nupur. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut |
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710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer Nature eBook | |
776 | 0 | 8 |
_iPrinted edition: _z9789819924226 |
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_iPrinted edition: _z9789819924240 |
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_iPrinted edition: _z9789819924257 |
856 | 4 | 0 | _uhttps://doi.org/10.1007/978-981-99-2423-3 |
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