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024 7 _a10.1007/978-981-99-2423-3
_2doi
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082 0 4 _a570.285
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100 1 _aPoluri, Krishna Mohan.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aProtein-Protein Interactions
_h[electronic resource] :
_bPathophysiological and Therapeutic Aspects: Volume II /
_cby Krishna Mohan Poluri, Khushboo Gulati, Deepak Kumar Tripathi, Nupur Nagar.
250 _a1st ed. 2023.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2023.
300 _aXVIII, 428 p. 1 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aChapter 1: Protein Networks in Human Disease -- Chapter 2: Protein-Protein Interactions in Cancer -- Chapter 3: Protein-Protein Interactions in Neurodegenerative Diseases -- Chapter 4: Protein-Protein Interactions in Immune Disorders and Inflammation -- Chapter 5: PPIs in Host-Pathogen Interactions -- Chapter 6: Drug Design methods to regulate protein-protein interactions -- Chapter 7: Small molecule inhibitors of Protein-Protein Interactions as Therapeutics.
520 _aThe second volume of the book-Protein-Protein Interactions (PPIs) provides an overview of various protein-protein interactions (PPIs) that are involved in various human diseases including cancer, neurodegenerative diseases, immune diseases, and inflammation. It summarizes the structure and ligand-based drug designing approaches for the discovery of small molecules that can inhibit PPIs in these diseases. The book discusses different computational and experimental tools that are used to determine the anomalous interactions underlying the diseases. Lastly, it also reviews the classical interactions between pathogens and hosts that are responsible for the pathophysiology of infectious diseases.
650 0 _aBioinformatics.
650 0 _aLife sciences.
650 0 _aMedicine
_xResearch.
650 0 _aBiology
_xResearch.
650 0 _aNeurosciences.
650 1 4 _aBioinformatics.
650 2 4 _aLife Sciences.
650 2 4 _aBiomedical Research.
650 2 4 _aNeuroscience.
700 1 _aGulati, Khushboo.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
700 1 _aTripathi, Deepak Kumar.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
700 1 _aNagar, Nupur.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789819924226
776 0 8 _iPrinted edition:
_z9789819924240
776 0 8 _iPrinted edition:
_z9789819924257
856 4 0 _uhttps://doi.org/10.1007/978-981-99-2423-3
912 _aZDB-2-SCS
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