000 04097nam a22005295i 4500
001 978-3-030-71737-7
003 DE-He213
005 20240423125359.0
007 cr nn 008mamaa
008 210805s2021 sz | s |||| 0|eng d
020 _a9783030717377
_9978-3-030-71737-7
024 7 _a10.1007/978-3-030-71737-7
_2doi
050 4 _aQH324.2-324.25
072 7 _aUY
_2bicssc
072 7 _aPS
_2bicssc
072 7 _aCOM082000
_2bisacsh
072 7 _aPSAX
_2thema
082 0 4 _a570.285
_223
245 1 0 _aEvolutionary Systems Biology
_h[electronic resource] :
_bAdvances, Questions, and Opportunities /
_cedited by Anton Crombach.
250 _a2nd ed. 2021.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2021.
300 _aX, 294 p. 49 illus., 31 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPart 1. Theory and philosophy -- Biology as a process and the consequences for studying it -- Capturing the genotype—phenotype map with the adaptive multiscape -- Evolution plays a high-dimensional game -- What is next for evolutionary systems biology? -- Part 2. Single celled organisms -- Experimental evolution of microbial host-parasite relations -- Engineering microbial communities that evolve in a spatial setting -- Sharing is caring: differential gene flow in microbial communities.-Synthetic biology to study the evolution of gene regulatory networks -- Evolution of stem cell differentiation -- The evolution of epigenetic switches and cellular clocks -- Part 3. Multicellular organisms -- Measuring the genotype—phenotype map in eukaryotes -- Pigment evolution in Drosophila fly species: time for theory? -- Birds of a feather: using experiment and theory to understand the evolution of feather patterning -- A regulatory network that explains both fish fins and mouse limbs -- Quantitative system driftof the fly body plan -- Part 4. Immunity and disease -- Of mice, men, and immunity -- Immunity as an evolving adaptive system -- Cancer is a microevolutionary systemic disease -- A systems approach to cancer.
520 _aThis new edition captures the advances made in the field of evolutionary systems biology since the publication of the first edition. The first edition focused on laying the foundations of evolutionary systems biology as an interdisciplinary field, where a way of thinking and asking questions is combined with a wide variety of tools, both experimental and theoretical/computational. Since publication of the first edition, evolutionary systems biology is now a well-known term describing this growing field. The new edition provides an overview of the current status and future developments of this interdisciplinary field. Chapters highlight several key achievements from the last decade and outline exciting new developments, including an understanding of the interplay between complexity and predictability in evolutionary systems, new viewpoints and methods to study organisms in evolving populations at the level of the genome, gene regulatory network, and metabolic network, and betteranalysis and modeling techniques that will open new avenues of scientific inquiry.
650 0 _aBioinformatics.
650 0 _aEvolution (Biology).
650 0 _aMicrobial genetics.
650 1 4 _aBioinformatics.
650 2 4 _aEvolutionary Biology.
650 2 4 _aMicrobial Genetics.
700 1 _aCrombach, Anton.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030717360
776 0 8 _iPrinted edition:
_z9783030717384
776 0 8 _iPrinted edition:
_z9783030717391
856 4 0 _uhttps://doi.org/10.1007/978-3-030-71737-7
912 _aZDB-2-SCS
912 _aZDB-2-SXCS
942 _cSPRINGER
999 _c177307
_d177307